Phytochemical, antioxidant, and antimicrobial effects of methanolic leaf extract of Rhazya stricta decne

Background: In this research, we investigated the antioxidant phytochemicals, antimicrobial and antibiofilm properties of methanolic leaf extract from Rhazya stricta.Methods: The main components R. stricta were confirmed through HPLC techniques. activity was examined by DPPD, ABTS, SOD Glutathione peroxidase assays.Results: results showed that better free radical scavenging with IC50 value 74.2 mg/ml DPPH assay. And tested high activities. analysis reveal presence rutin. Antibacterial revealed had higher anti-bacterial against multi drug resistant microbes namely, Bacillus subtilis (3.51 mm), Staphylococcus aureus (1.29 Escherichia coli (3.39 Klebsiella pneumoniae (2.03 Pseudomonas aeruginosa (5.73 mm). addition, strong potential at 100 µg/ml.Conclusions: Overall, significant capacity highly inhibit bacterial pathogens.